hsCRP (High Sensitivity CRP) Test |#MTP|

High-sensitivity C-reactive protein (hs-CRP) is a measure of baseline concentrations and a marker of chronic inflammation. It predicts the risk of heart disease development in healthy persons, as well as the risk of myocardial infarction in patients with acute coronary syndromes. CRP, or C-reactive protein, is typically measured at levels between 3 and 5 mg/L, whereas hs-CRP can detect levels as low as about 0.3 mg/L. Because of its increased sensitivity, hs-CRP is utilised to identify minor chronic inflammation. The higher your hs-CRP levels, the higher your levels of inflammation.

Written by: Dr Mahak Sharma, MBBS, MD, Dept. of Heamatology 

Reasons for Undergoing the HsCRP Test

The high-sensitivity CRP (hs-CRP) test is a valuable diagnostic tool that serves several important purposes. Here are the key reasons for undergoing this test:

• Assessing cardiovascular risk: The hs-CRP test helps evaluate the risk of developing coronary artery disease, heart attacks, and strokes, as high levels of hs-CRP are associated with increased cardiovascular risk.
• Diagnosing chronic inflammatory diseases: The test aids in the diagnosis and monitoring of chronic inflammatory conditions such as rheumatoid arthritis, lupus, and inflammatory bowel disease.
• Monitoring infection and inflammation: The hs-CRP blood test is useful for checking inflammation that may be caused by an infection or injury, as CRP levels rise in response to inflammatory processes.
• Risk stratification: For individuals who have already experienced a heart attack, the test assesses the risk of a second event, as high hs-CRP levels are linked to a higher risk of recurrent cardiovascular issues.
• General health screening: For individuals with an intermediate risk of heart disease (typically a 10-20% chance of having a heart attack within the next 10 years), the test provides additional insights into their cardiovascular health.

List of Parameters Considered During HsCRP Test

The high-sensitivity CRP test focuses on a specific parameter to provide valuable insights into an individual's health. The key parameter measured is:

• C-Reactive Protein (CRP) Levels: The hs-CRP test measures the concentration of CRP in the blood, which is a protein produced by the liver in response to inflammation. The levels are categorised as follows:
  • Low Levels: Less than 1 mg/L or 2 mg/L, indicating a lower risk of heart disease.
  • Moderate Levels: 1-3 mg/L, suggesting an average or moderate risk of heart disease.
  • High Levels: Greater than 3 mg/L or 2 mg/L, indicating a higher risk of heart disease, including heart attacks and strokes.